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The detrimental effect of increased endometrial thickness on implantation and pregnancy rates and outcome in an in vitro fertilization program
Plain-language guide to PMID 9935132 (1999): clinical trial study of hCG (human chorionic gonadotropin) in 623 patients, endometriosis.
Key Facts
- PMID
- 9935132
- Journal
- Fertility and sterility
- Year
- 1999
- Study type
- Clinical Trial
- Authors
- Weissman A et al. (3 authors)
- DOI
- 10.1016/s0015-0282(98)00413-0
What This Study Did, in Plain Language
What Was Tested
This clinical trial paper looks at hCG (human chorionic gonadotropin) in the context of endometriosis.
To determine whether there is a maximal value for endometrial thickness, as measured on the day of hCG administration, above which implantation and pregnancy are unlikely to occur.
Who Took Part
The study group was 623 patients.
The age groups tagged for this paper are adults, women only.
A total of 809 IVF cycles in 623 patients resulting in ET.
How the Study Was Run
A university-based tertiary care center for assisted reproductive technology.
Endometrial thickness was measured by means of transvaginal ultrasound on the day of hCG administration.
Cycles were divided into two groups based on endometrial thickness.
What Was Measured
Topics PubMed links to this paper include Chorionic Gonadotropin, Embryo Implantation, Endometrium, Estradiol, Fertilization in Vitro and Pregnancy Outcome.
What This Means in Plain Language
This is a clinical trial of hCG (human chorionic gonadotropin) in 623 patients in people with endometriosis.
With several hundred people or more, it is a fairly large study for this kind of research.
Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 1999 (Fertility and sterility), a journal based in United States.
More context: the hCG (human chorionic gonadotropin) compound page, Endometriosis research.
Our Notes on the Compound
hCG (human chorionic gonadotropin): An LH analog that drives Leydig-cell testosterone production.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.