What is Cortagen?
A synthetic four-amino-acid peptide (Ala-Glu-Asp-Pro) investigated for effects on nerve tissue and gene expression.
Cortagen in the library · Bioregulator Peptides · Human Trials · What are peptides?
0 registered trials · 0 indexed papers · 3 human / 12 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
Cortagen is characterized as a synthetic four-amino-acid peptide (Ala-Glu-Asp-Pro, AEDP) investigated for effects on nerve tissue and gene expression. It was developed through directed synthesis informed by the brain cortex peptide preparation Cortexin, within the Khavinson peptide bioregulator research program.
Its research history includes rat nerve-injury experiments, mouse studies and early patient reports in a patent, described as a more limited foundation than the confident claims about memory, brain fog and “brain repair” frequently attached to it.
Overview (as described)
- Some experiments suggest biological activity; whether a particular product improves a meaningful outcome in people at an acceptable level of risk is described as unresolved.
More cited research
- EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE "OLD" CHROMATIN (2023, human observational)
- EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON "AGED" HETEROCHROMATIN (2020, human observational)
- Effects of short peptides on lymphocyte chromatin in senile subjects (2004, human observational)
- Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray (2004, animal)
- [Effects of epithalon and cortagene on immunity and hemostasis in neonatally hypophysectomized chicken and old birds] (2008, animal)
- Effects of bioactive tetrapeptides on free-radical processes (2007, animal)
- Production of lymphocyte-activating factors by mouse macrophages during aging and under the effect of short peptides (2006, animal)
Related compounds
- Pinealon
- Adamax
- Bromantane (non-peptide)
- Bronchogen
- Cardiogen
- Cartalax
- Cerebrolysin
- Chonluten
- Colivelin
- Crystagen
FAQ
What is Cortagen?
A synthetic four-amino-acid peptide (Ala-Glu-Asp-Pro) investigated for effects on nerve tissue and gene expression.
How many registered human trials study Cortagen?
The PeptideWhiz trial index lists 0 registered trials for Cortagen.
How much published research exists on Cortagen?
By study type, PeptideWhiz counts 3 human and 12 animal studies on Cortagen.
Which conditions is Cortagen researched for?
No condition pages are linked to this compound yet.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).