What is AOD-9604?
A modified fragment of growth hormone that acts through a different pathway than GH.
AOD-9604 in the library · Healing & Repair Peptides · Metabolic & Weight Peptides · Human Trials · What are peptides?
0 registered trials · 0 indexed papers · 7 human / 4 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
A modified fragment of growth hormone that acts through a different pathway than GH. It doesn't carry GH's insulin or growth effects.
Additional points (as described)
- The last 15 amino acids of GH without the growth portion. It acts on fat-cell β3 receptors without affecting glucose or insulin, but it's weak for fat loss compared with tesamorelin.
- Its main use is cartilage: chondrocyte growth, type II collagen and aggrecan. Oral high-molecular-weight hyaluronic acid (and quality stem cells) is described alongside it before considering joint replacement.
- Joint signaling depends on loading (Wolff's law), so bad mechanics undermine cartilage.
More cited research
- AOD-9604 does not influence the WADA hGH isoform immunoassay (2013, human observational)
- Gateways to clinical trials (2005, human observational)
- Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model (2015, animal)
- The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice (2001, animal)
- Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone (2000, animal)
- Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment (2001, animal)
Conditions researched
Related compounds
- Amycretin
- Ecnoglutide
- L-Carnitine
- Liraglutide
- Orforglipron (Foundayo, non-peptide)
- Retatrutide
- Semaglutide
- Tirzepatide
- 5-Amino-1MQ
- ACTH (Corticotropin)
FAQ
What is AOD-9604?
A modified fragment of growth hormone that acts through a different pathway than GH.
How many registered human trials study AOD-9604?
The PeptideWhiz trial index lists 0 registered trials for AOD-9604.
How much published research exists on AOD-9604?
By study type, PeptideWhiz counts 7 human and 4 animal studies on AOD-9604.
Which conditions is AOD-9604 researched for?
Osteoarthritis, cartilage loss & avoiding joint replacement.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).