What is Selank?

A synthetic heptapeptide developed from tuftsin, studied mainly for anxiety; not an FDA-approved anxiety medicine.

Selank in the library · · Human Trials · What are peptides?

0 registered trials · 3 indexed papers · 11 human / 51 animal studies

From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.

What it is

Selank is described as a synthetic peptide studied mainly for anxiety. Small human studies have reported improvements but are described as not settling whether it is a dependable long-term treatment. It is described as not an FDA-approved anxiety medicine.

Structure (as described)

  • A seven-amino-acid peptide (heptapeptide) developed from tuftsin, a naturally occurring immune-system peptide, by adding three amino acids. Its sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro. That origin explains the interest in nervous-system and immune effects.
  • It is described as anxiolytic (intended to reduce anxiety) or nootropic (proposed to improve cognition); those labels describe the questions investigated, not the strength of the evidence.

Evidence (as described)

  • Published clinical reports offer preliminary support, mostly from relatively small Russian-language studies; English abstracts describe comparisons with benzodiazepines rather than a large, independently replicated placebo-controlled program.

Peer-reviewed studies (3)

PaperAuthorsJournalYearType
[Optimization of the treatment of anxiety disorders with selank]Medvedev VE et al.Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova2015Randomized Controlled Trial
[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders]Medvedev VE et al.Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova2014Clinical Trial
[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]Zozulia AA et al.Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova2008Randomized Controlled Trial

More cited research

Conditions researched

Related compounds

FAQ

What is Selank?

A synthetic heptapeptide developed from tuftsin, studied mainly for anxiety; not an FDA-approved anxiety medicine.

How many registered human trials study Selank?

The PeptideWhiz trial index lists 0 registered trials for Selank.

How much published research exists on Selank?

The PeptideWhiz paper index links 3 PubMed papers to Selank; by study type, 11 human and 51 animal studies.

Which conditions is Selank researched for?

Anxiety and panic, Cognition, focus & brain performance, Fight-or-flight and nervous system overdrive.

Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).

Reported dosing ranges from research