What is Thymogen?
A dipeptide (Glu-Trp, also called oglufanide) investigated for effects on immune signaling; not the same molecule as thymosin alpha-1.
Thymogen in the library · Bioregulator Peptides · Human Trials · What are peptides?
0 registered trials · 9 indexed papers · 49 human / 40 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
Thymogen is described as a short peptide made from glutamic acid and tryptophan, commonly written Glu-Trp, that has been investigated for effects on immune signaling. Chemical references also call it oglufanide; the National Cancer Institute is described as listing Thymogen and IM862 as names associated with oglufanide disodium, the salt form studied clinically.
It is described as not the same molecule as thymosin alpha-1; the word “immune” does not make their evidence interchangeable. Research spans cells, animals and clinical studies in specific populations and includes a negative trial that belongs in the discussion.
Peer-reviewed studies (9)
More cited research
- [Effect of thymagen, thymalin and vilosen on the cAMP and cGMP levels and phosphodiesterase activity in spleen lymphocytes during sensitization and anaphylactic (1991, animal)
- [Inhibiting effect of thymogen on the development of tumors of the esophagus and forestomach induced by N-nitrososarcosine ethyl ester in rats] (1989, animal)
- [Effects of mercazolyl and L-thyroxine on the antiedematous activity of immunotropic preparations during development of toxic brain edema and swelling] (2008, animal)
- Immunomodulatory synthetic dipeptide L-Glu-L-Trp slows down aging and inhibits spontaneous carcinogenesis in rats (2000, animal)
Conditions researched
Related compounds
- Crystagen
- LL-37 (cathelicidin)
- Thymalin
- Thymopentin
- Thymosin Alpha-1
- Thymulin
- Vilon
- ACTH (Corticotropin)
- Alpha-MSH
- Angiotensin II
FAQ
What is Thymogen?
A dipeptide (Glu-Trp, also called oglufanide) investigated for effects on immune signaling; not the same molecule as thymosin alpha-1.
How many registered human trials study Thymogen?
The PeptideWhiz trial index lists 0 registered trials for Thymogen.
How much published research exists on Thymogen?
The PeptideWhiz paper index links 9 PubMed papers to Thymogen; by study type, 49 human and 40 animal studies.
Which conditions is Thymogen researched for?
Skin, hair loss, wounds & mast-cell/histamine reactivity.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).