Growth Hormone Secretagogues

Name: Growth Hormone Secretagogues (PeptideWhiz research library)
Creator: PeptideWhiz

Growth Hormone Secretagogues in the PeptideWhiz research library: 18 compounds, each linked to registered human trials, peer-reviewed studies and related conditions. Grouped by the library's own research tags.

A to Z Index · Healing & Repair Peptides · Growth Hormone Secretagogues · Bioregulator Peptides · Cosmetic & Skin Peptides · Metabolic & Weight Peptides · Human Trials

CJC-1295 (no DAC) (with/without DAC) + Ipamorelin Library entryGH secretagogues, preferred over exogenous HGH because the body keeps its pulsatile release and feedback control.Conditions: Muscle gain, sarcopenia & building muscle after 40, Fat loss, obesity & body recomposition, Low testosterone (without or alongside TRT), Fatigue & low energy (incl. midlife)
CJC-1295 (no DAC), Mod GRF 1-29 Library entryA modified GHRH(1-29) with four amino-acid swaps for stability; short-acting, unlike CJC-1295 with DAC.Conditions: Anti-aging & longevity, Fat loss, obesity & body recomposition, Low testosterone (without or alongside TRT), Lyme disease & chronic infections
CJC-1295 with DAC Library entryA long-acting GHRH analog that binds albumin; human studies showed GH and IGF-1 rises lasting days after one injection.Conditions: Lyme disease & chronic infections, Multiple sclerosis
Exogenous HGH, sermorelin & older GHRPs (why they're passed over)Library entryConstant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.Conditions: Fat loss, obesity & body recomposition, Multiple sclerosis, Muscle gain, sarcopenia & building muscle after 40, Anti-aging & longevity
GHRP-1 Library entryAn early heptapeptide growth hormone secretagogue, studied in the 1990s alongside GHRP-2 and GHRP-6.Conditions: Kidney protection (CKD, diabetic kidney, lupus kidney)
GHRP-2 Library entryA synthetic growth hormone secretagogue that activates the ghrelin receptor and can increase appetite.Conditions: Fat loss, obesity & body recomposition
GHRP-6 Library entryAn early synthetic hexapeptide ghrelin-receptor agonist that releases growth hormone and strongly increases appetite.Conditions: Anti-aging & longevity, Concussion, traumatic brain injury & stroke recovery, Fat loss, obesity & body recomposition, Insulin resistance, prediabetes & type 2 diabetes
Growth Hormone Peptide Blends Library entryOne page for the many sold pairings of a GHRH-type peptide (CJC-1295 (no DAC), sermorelin, tesamorelin) with a ghrelin-receptor agonist (ipamorelin, GHRP-2, GHRP-6, hexarelin).
Hexarelin Library entryA potent synthetic hexapeptide GH secretagogue, also studied for direct heart effects via the CD36 receptor.Conditions: Anti-aging & longevity, Atherosclerosis, cardiovascular disease & high blood pressure, Fat loss, obesity & body recomposition, Heart repair: after heart attack, heart failure & enlarged heart
IGF-1 DES Library entryA shortened form of insulin-like growth factor 1, des(1-3)IGF-I, that can be more potent than native IGF-1 in some laboratory experiments.
Ipamorelin Library entryA selective ghrelin-receptor agonist (growth hormone secretagogue) studied in human pharmacology and a postoperative ileus trial.Conditions: Anti-aging & longevity, Fat loss, obesity & body recomposition, Fatigue & low energy (incl. midlife), Gut: IBD (Crohn's, colitis), leaky gut, IBS & ulcers
Mecasermin (rhIGF-1)Library entryFDA-approved recombinant human IGF-1 for severe primary IGF-1 deficiency in children; distinct from IGF-1 LR3 and IGF-1 DES.Conditions: Autism support, Concussion, traumatic brain injury & stroke recovery, Fat loss, obesity & body recomposition, Heart repair: after heart attack, heart failure & enlarged heart
MGF (Mechano Growth Factor)Library entryA name tied to an IGF-1 splice variant (IGF-1Ec) and to a short E-domain peptide, studied in muscle biology.
MK-677 (Ibutamoren)Library entryAn oral, non-peptide ghrelin-receptor agonist.Conditions: Muscle gain, sarcopenia & building muscle after 40, Menopause & perimenopause, Multiple sclerosis, Anti-aging & longevity
PEG-MGF Library entryA pegylated form of the mechano growth factor peptide discussed in muscle research; FDA identifies human-safety gaps.
Relamorelin Library entryA potent ghrelin-receptor agonist studied for diabetic gastroparesis and constipation through phase 2b/3.Conditions: Delayed gastric emptying on GLP-1 medicines, Insulin resistance, prediabetes & type 2 diabetes, Parkinson's disease
Sermorelin Library entryThe first 29 amino acids of growth hormone-releasing hormone; once FDA-approved (Geref) and now mainly compounded.Conditions: Fat loss, obesity & body recomposition, Anti-aging & longevity, Thyroid problems
Tesamorelin Library entryGH pulse → liver IGF-1 → mTOR and PI3K-AKT (muscle).Conditions: Fat loss, obesity & body recomposition, Insulin resistance, prediabetes & type 2 diabetes, Muscle gain, sarcopenia & building muscle after 40, Dementia, Alzheimer's & cognitive decline

Research and education only. Not medical advice. Summaries and source links only, no dosing advice.