What is Noopept (non-peptide)?
A Russian nootropic dipeptide-like compound sold next to Semax and Selank; it is a small molecule, not a true peptide.
Noopept (non-peptide) in the library · · Human Trials · What are peptides?
0 registered trials · 3 indexed papers · 3 human / 9 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
Noopept is described as a proline-containing dipeptide derivative developed in Russia as a nootropic (Ostrovskaya et al., 2002).
Mechanism (as described)
- It is described as converting in the body to cycloprolylglycine and as affecting neurotrophic factors and glutamate signaling in animal studies.
Evidence (as described)
- Small Russian studies in mild cognitive impairment after injury, vascular disease or stroke reported benefit (Bochkarev et al., 2008; Amelin et al., 2011). High-quality trials are lacking.
Status
Registered in Russia; not approved in the US or EU.
Peer-reviewed studies (3)
| Paper | Authors | Journal | Year | Type |
|---|---|---|---|---|
| [Noopept in the treatment of mild cognitive impairment in patients with stroke] | Amelin AV et al. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova | 2011 | Clinical Trial |
| [Clinical and electroencephalographic characteristic of noopept in patients with mild cognitive impairment of posttraumatic and vascular origin] | Bochkarev VK et al. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova | 2008 | Clinical Trial |
| [Meteoadaptogenic properties of peptide drugs in healthy volunteers] | Shabanov PD et al. | Eksperimental'naia i klinicheskaia farmakologiia | 2007 | Controlled Clinical Trial |
More cited research
- Gateways to clinical trials (2005, human observational)
- Effects of noopept on cognitive functions and pubertal process in rats with diabetes (2019, animal)
- [Effects of nootropic drugs on behavior of BALB/c and C57BL/6 mice in the exploratory cross-maze test] (2012, animal)
- [Peptidergic modulation of the hippocampus synaptic activity] (2011, animal)
- [Studying specific effects of nootropic drugs on glutamate receptors in the rat brain] (2011, animal)
Conditions researched
Related compounds
- ACTH (Corticotropin)
- ANP (Atrial Natriuretic Peptide)
- Angiotensin II
- BNP (Nesiritide)
- Bromantane (non-peptide)
- Calcitonin
- Cerebrolysin
- Cyanocobalamin (Vitamin B12)
- Davunetide
- Desmopressin
FAQ
What is Noopept (non-peptide)?
A Russian nootropic dipeptide-like compound sold next to Semax and Selank; it is a small molecule, not a true peptide.
How many registered human trials study Noopept (non-peptide)?
The PeptideWhiz trial index lists 0 registered trials for Noopept (non-peptide).
How much published research exists on Noopept (non-peptide)?
The PeptideWhiz paper index links 3 PubMed papers to Noopept (non-peptide); by study type, 3 human and 9 animal studies.
Which conditions is Noopept (non-peptide) researched for?
Concussion, traumatic brain injury & stroke recovery, Dementia, Alzheimer's & cognitive decline.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).