What is ANP (Atrial Natriuretic Peptide)?
A 28-amino-acid heart hormone that relaxes blood vessels and increases salt excretion; carperitide is a recombinant form.
ANP (Atrial Natriuretic Peptide) in the library · · Human Trials · What are peptides?
3 registered trials · 1166 indexed papers · 1244 human / 207 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
A 28-amino-acid heart hormone that relaxes blood vessels and increases salt excretion; carperitide is a recombinant form.
Type: Natriuretic peptide.
Definition (National Library of Medicine)
“A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight peptides derived from a common precursor and secreted mainly by the heart atrium. All these peptides share a sequence of about 20 amino acids.”
- MeSH: Atrial Natriuretic Factor
Human research
The registered human trials and peer-reviewed human studies linked below are listed from ClinicalTrials.gov and PubMed. A study is linked only when ANP (Atrial Natriuretic Peptide) is one of its interventions, or is named in the study title or subject headings.
Listing a study does not mean it showed a benefit, and it is not medical advice.
Registered human trials (3)
| Trial | Phase | Status | Year | Enrolled |
|---|---|---|---|---|
| The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure | Phase 4 | terminated | 2009 | 200 |
| Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure | Phase 2 | completed | 2004 | 162 |
| Prevention Of Nephrotoxicity Following Bone Marrow Transplantation Using Urodilatin and Mannitol | Phase 2 | completed | 2003 | 20 |
Peer-reviewed studies (1166)
More cited research
- Plasma levels of atrial natriuretic peptide in severe burn injury (2000, human observational)
- Atrial natriuretic peptide in pregnancy: response to oral sodium supplementation (1992, human observational)
- The circadian rhythm of atrial natriuretic peptide, vasoactive intestinal peptide, beta-endorphin and cortisol in healthy young and elderly subjects (1992, human observational)
- [The circadian rhythm of plasma vasoactive intestinal peptide, atrial natriuretic peptide, renin activity, aldosterone and cortisol in heart transplantation. Th (1992, human observational)
- Ghrelin suppresses water intake with a different physiological significance from atrial natriuretic peptide in conscious seawater-acclimated eels (2025, animal)
- Atrial natriuretic factor stimulates efflux of cAMP in rat exocrine pancreas via multidrug resistance-associated proteins (2011, animal)
- Regulation of atrial natriuretic peptide secretion by cholinergic and PACAP neurons of the gastric antrum (2003, animal)
- Involvement of K+ channels in the relaxant effect of vasoactive intestinal peptide and atrial natriuretic peptide in isolated guinea-pig trachea (1997, animal)
Conditions researched
- Anemia
- Anti-aging & longevity
- Anxiety and panic
- Atherosclerosis, cardiovascular disease & high blood pressure
- Candida & persistent bacterial infections
- Chronic and systemic inflammation
- Concussion, traumatic brain injury & stroke recovery
- Dementia, Alzheimer's & cognitive decline
- Fat loss, obesity & body recomposition
- Fatty liver & elevated liver enzymes
- Heart repair: after heart attack, heart failure & enlarged heart
- High-demand jobs: military, fire, police, EMT (and combat-sport athletes)
- Immune system (general)
- Insulin resistance, prediabetes & type 2 diabetes
- Kidney protection (CKD, diabetic kidney, lupus kidney)
- Low blood pressure and orthostatic hypotension
- Lung health, asthma & COPD
- Lymphedema and swelling
- Menopause & perimenopause
- Osteoarthritis, cartilage loss & avoiding joint replacement
- PCOS
- PMDD (premenstrual dysphoric disorder)
- Post-surgical inflammation and surgery recovery
- POTS and dysautonomia
- Pregnancy and breastfeeding: safety notes
- Rheumatoid arthritis
- Sleep apnea (obstructive)
- Sleep problems (incl. insomnia on peptides)
- Thyroid problems
Related compounds
- ACTH (Corticotropin)
- BNP (Nesiritide)
- L-Carnitine
- Vasopressin
- Endothelin-1
- Glutathione
- Ghrelin
- IGF-1 LR3
- Parathyroid Hormone (PTH 1-84)
- Angiotensin II
FAQ
What is ANP (Atrial Natriuretic Peptide)?
A 28-amino-acid heart hormone that relaxes blood vessels and increases salt excretion; carperitide is a recombinant form.
How many registered human trials study ANP (Atrial Natriuretic Peptide)?
The PeptideWhiz trial index lists 3 registered trials for ANP (Atrial Natriuretic Peptide), the most recent from 2009.
How much published research exists on ANP (Atrial Natriuretic Peptide)?
The PeptideWhiz paper index links 1166 PubMed papers to ANP (Atrial Natriuretic Peptide); by study type, 1244 human and 207 animal studies.
Which conditions is ANP (Atrial Natriuretic Peptide) researched for?
Anemia, Anti-aging & longevity, Anxiety and panic, Atherosclerosis, cardiovascular disease & high blood pressure, Candida & persistent bacterial infections, Chronic and systemic inflammation, Concussion, traumatic brain injury & stroke recovery, Dementia, Alzheimer's & cognitive decline, Fat loss, obesity & body recomposition, Fatty liver & elevated liver enzymes, Heart repair: after heart attack, heart failure & enlarged heart, High-demand jobs: military, fire, police, EMT (and combat-sport athletes), Immune system (general), Insulin resistance, prediabetes & type 2 diabetes, Kidney protection (CKD, diabetic kidney, lupus kidney), Low blood pressure and orthostatic hypotension, Lung health, asthma & COPD, Lymphedema and swelling, Menopause & perimenopause, Osteoarthritis, cartilage loss & avoiding joint replacement, PCOS, PMDD (premenstrual dysphoric disorder), Post-surgical inflammation and surgery recovery, POTS and dysautonomia, Pregnancy and breastfeeding: safety notes, Rheumatoid arthritis, Sleep apnea (obstructive), Sleep problems (incl. insomnia on peptides), Thyroid problems.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).