Home › Peptides A to Z › BNP (Nesiritide)What is BNP (Nesiritide)? B-type natriuretic peptide, a 32-amino-acid heart hormone; nesiritide (Natrecor) is a recombinant form used in acute heart failure.
BNP (Nesiritide) in the library · · Human Trials · What are peptides?
81 registered trials · 2107 indexed papers · 2320 human / 32 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is B-type natriuretic peptide, a 32-amino-acid heart hormone; nesiritide (Natrecor) is a recombinant form used in acute heart failure.
Type: Natriuretic peptide.
Definition (National Library of Medicine) “A peptide that is secreted by the brain and the heart atria, stored mainly in cardiac ventricular myocardium. It can cause natriuresis; diuresis; vasodilation; and inhibits secretion of renin and aldosterone. It improves heart function. It contains 32 amino acids.”
MeSH: Natriuretic Peptide, Brain Human research The registered human trials and peer-reviewed human studies linked below are listed from ClinicalTrials.gov and PubMed. A study is linked only when BNP (Nesiritide) is one of its interventions, or is named in the study title or subject headings.
Listing a study does not mean it showed a benefit, and it is not medical advice.
Registered human trials (81) Peer-reviewed studies (2107) Paper Authors Journal Year Type Using dapagliflozin to reduce symptoms in transthyretin cardiac amyloidosis: An n-of-1 trial series pilot study Håkansson E et al. PloS one 2026 Clinical Trial Measuring long-term physical activity in patients with heart failure and its relation to health-related outcomes Leps C et al. ESC heart failure 2026 Observational Study Can Biomarker-Based Monitoring Detect the Early Development of Diastolic Dysfunction During Chemotherapy? Farcaş AD et al. Medicina (Kaunas, Lithuania) 2026 Observational Study Effect of Continuous Positive Airway Pressure on Left Atrial Volume Index in Patients With Stroke and Obstructive Sleep Apnea: A Randomized Trial Lin CH et al. Journal of the American Heart Association 2026 Randomized Controlled Trial Subclinical cardiac involvement during diabetic ketoacidosis at type 1 diabetes onset in youth: biomarker elevation, altered diastolic filling, and reduced global longitudinal strain: a prospective cohort study Weiskorn J et al. Cardiovascular diabetology 2026 Observational Study Comparing the Prognostic Performance Using Various Diagnostic Scoring Systems in Heart Failure With Preserved Ejection Fraction: Insights From the Nationwide Prospective Registry Chang HY et al. Journal of the American Heart Association 2026 Observational Study Early urinary sodium vs B-type natriuretic peptide for predicting 30-day outcomes in acute decompensated heart failure: a prospective cohort study Acara AC et al. Croatian medical journal 2026 Observational Study Natriuretic Peptide and Transthyretin and Their Relationship With Clinical Outcomes: Results From ATTRIBUTE-CM, a Randomized Controlled Trial Ilonze OJ et al. Journal of the American Heart Association 2026 Randomized Controlled Trial Integrated Cardiopulmonary Profile as an Additive Signal in Patients Evaluated for Suspected Newly Detected Atrial Fibrillation Kundnani NR et al. Medical sciences (Basel, Switzerland) 2026 Observational Study NT-proBNP as a marker of coronary artery disease burden in chronic coronary syndromes Schivalocchi M et al. International journal of cardiology 2026 Observational Study Risk factors for carfilzomib-related cardiovascular adverse events in Chinese patients with multiple myeloma: A real-world retrospective cohort study Wei XC et al. The Journal of international medical research 2026 Observational Study Natriuretic peptide responses to exercise in HFpEF diagnosis: a pilot study van Ommen AMLN et al. Open heart 2026 Observational Study Impact of estimated total blood volume on NT-proBNP response to angiotensin receptor-neprilysin inhibition in acute heart failure: Insights from the PREMIER study Nogi K et al. American heart journal 2026 Randomized Controlled Trial Temporal changes in BNP levels and their prognostic impact on future cardiac events in patients undergoing transcatheter aortic valve implantation Mizutani K et al. International journal of cardiology 2026 Observational Study Pulmonary congestion assessed by lung ultrasound in stable ambulatory patients with heart failure and preserved ejection fraction in primary care Leceaga-Gaztambide E et al. Family practice 2026 Observational Study Cardiotoxicity Associated with Antineoplastic Therapy: A Multidisciplinary Approach to Personalized Monitoring Using Radionuclide Imaging and Molecular Biomarkers Kajanto LA et al. Chirurgia (Bucharest, Romania : 1990) 2026 Observational Study Atrial Cardiopathy in Embolic Strokes of Undetermined Source Lalitha LP et al. Neurology India 2026 Observational Study Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study Akhmedova N et al. Renal failure 2026 Observational Study Mapping the Heart-Brain Continuum beyond Heart Failure: Why Neurology Matters Zhang X et al. The Journal of neuroscience : the official journal of the Society for Neuroscience 2026 Observational Study [Errors in the diagnosis of chronic heart failure among outpatient elderly patients with type 2 diabetes mellitus.] Pervyshin NA et al. Advances in gerontology = Uspekhi gerontologii 2026 Observational Study Heart Failure Medication Withdrawal in Patients With Improved Cardiac Function After Atrial Fibrillation Ablation: The DEFINITION-AF Pilot Randomized Clinical Trial Li S et al. JAMA network open 2026 Randomized Controlled Trial Efficacy and safety of vericiguat in patients with heart failure with reduced ejection fraction and asymptomatic hypotension: insights from a multicenter observational cohort study Tian J et al. BMC cardiovascular disorders 2026 Observational Study Real-world burden of cardiovascular events following immune checkpoint inhibitor therapy: impact on mortality and treatment resumption in 29,503 patients Rigaux C et al. Lung cancer (Amsterdam, Netherlands) 2026 Observational Study Genotype Predicts Heart Failure Independent of LVEF, Peak VO(2), and NT-proBNP Levels in Hypertrophic Cardiomyopathy Bakalakos A et al. JACC. Heart failure 2026 Observational Study Cardiac biomarkers combined with neuroimaging localization predict long-term outcomes in acute stroke patients Tüner H et al. Scientific reports 2026 Observational Study Cardiac Biomarkers to Refine Pretest Probability for Coronary Obstruction and Predict Survival After Revascularization in Chronic Coronary Syndrome Teren A et al. Journal of the American Heart Association 2026 Observational Study Recombinant human brain natriuretic peptide for the recovery stage of septic shock: an interventional study protocol Luo JC et al. BMJ open 2026 Clinical Study Predictive efficacy of PASP combined with NT-proBNP for outcomes in pregnant women with severe cardiovascular disease: a single-centre retrospective observational study Tian D et al. BMC pregnancy and childbirth 2026 Observational Study Six-month effects of liraglutide and dapagliflozin on lipid profile, cardiovascular risk, and NT-proBNP levels in patients with metabolic dysfunction-associated steatotic liver disease Cherniavskyi V et al. Wiadomosci lekarskie (Warsaw, Poland : 1960) 2026 Randomized Controlled Trial Sedentary behavior with atrial fibrillation-related biomarkers in overweight or obese adults Li L et al. BMC cardiovascular disorders 2026 Randomized Controlled Trial
More cited research Brain Natriuretic Peptide as the long-term cause of mortality in patients with cardiovascular disease: a retrospective cohort study (2015, human observational)A Canadian context for the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF) trial (None, human trial (non-randomized))A Pilot Study of the Association of Amino-Terminal Pro-B-Type Natriuretic Peptide and Severity of Illness in Pediatric Septic Shock (None, human observational)A Randomized Trial of Reminders of Past High BNP to Increase Measurement of LVEF (None, human RCT)Brain natriuretic peptide stimulates K and Cl secretion across porcine distal colon epithelium (1991, animal)The vasoactive effects of bradykinin, vasoactive intestinal peptide, calcitonin gene-related peptide and neuropeptide Y depend on the perivascular tissue in por (2024, animal)Nicotinamide riboside kinase-2 inhibits JNK pathway and limits dilated cardiomyopathy in mice with chronic pressure overload (2022, animal)Nicotinamide Riboside Alleviates Cardiac Dysfunction and Remodeling in Pressure Overload Cardiac Hypertrophy (2021, animal)Conditions researched Acid reflux and GERD Anemia Anti-aging & longevity Atherosclerosis, cardiovascular disease & high blood pressure Chronic and systemic inflammation Cognition, focus & brain performance Concussion, traumatic brain injury & stroke recovery Dementia, Alzheimer's & cognitive decline Fat loss, obesity & body recomposition Fatigue & low energy (incl. midlife) Gout Gum disease (periodontal) & oral health Gut: IBD (Crohn's, colitis), leaky gut, IBS & ulcers Heart repair: after heart attack, heart failure & enlarged heart Immune system (general) Insulin resistance, prediabetes & type 2 diabetes Kidney protection (CKD, diabetic kidney, lupus kidney) Low blood pressure and orthostatic hypotension Lung health, asthma & COPD Lymphedema and swelling Migraine Multiple sclerosis Muscle gain, sarcopenia & building muscle after 40 Neuropathy and CRPS Pancreatitis (after the acute phase) Post-surgical inflammation and surgery recovery Pregnancy and breastfeeding: safety notes Psoriasis and psoriatic arthritis Rheumatoid arthritis Skin, hair loss, wounds & mast-cell/histamine reactivity Sleep apnea (obstructive) Sleep problems (incl. insomnia on peptides) Swollen feet and ankles Thick blood and blood clots Thyroid problems Related compounds FAQ What is BNP (Nesiritide)? B-type natriuretic peptide, a 32-amino-acid heart hormone; nesiritide (Natrecor) is a recombinant form used in acute heart failure.
How many registered human trials study BNP (Nesiritide)? The PeptideWhiz trial index lists 81 registered trials for BNP (Nesiritide), the most recent from 2026.
How much published research exists on BNP (Nesiritide)? The PeptideWhiz paper index links 2107 PubMed papers to BNP (Nesiritide); by study type, 2320 human and 32 animal studies.
Which conditions is BNP (Nesiritide) researched for? Acid reflux and GERD, Anemia, Anti-aging & longevity, Atherosclerosis, cardiovascular disease & high blood pressure, Chronic and systemic inflammation, Cognition, focus & brain performance, Concussion, traumatic brain injury & stroke recovery, Dementia, Alzheimer's & cognitive decline, Fat loss, obesity & body recomposition, Fatigue & low energy (incl. midlife), Gout, Gum disease (periodontal) & oral health, Gut: IBD (Crohn's, colitis), leaky gut, IBS & ulcers, Heart repair: after heart attack, heart failure & enlarged heart, Immune system (general), Insulin resistance, prediabetes & type 2 diabetes, Kidney protection (CKD, diabetic kidney, lupus kidney), Low blood pressure and orthostatic hypotension, Lung health, asthma & COPD, Lymphedema and swelling, Migraine, Multiple sclerosis, Muscle gain, sarcopenia & building muscle after 40, Neuropathy and CRPS, Pancreatitis (after the acute phase), Post-surgical inflammation and surgery recovery, Pregnancy and breastfeeding: safety notes, Psoriasis and psoriatic arthritis, Rheumatoid arthritis, Skin, hair loss, wounds & mast-cell/histamine reactivity, Sleep apnea (obstructive), Sleep problems (incl. insomnia on peptides), Swollen feet and ankles, Thick blood and blood clots, Thyroid problems.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).