What is Bombesin?
A 14-amino-acid peptide first found in frog skin; its analogs are studied as imaging tracers for some cancers.
Bombesin in the library · · Human Trials · What are peptides?
10 registered trials · 35 indexed papers · 103 human / 304 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
A 14-amino-acid peptide first found in frog skin; its analogs are studied as imaging tracers for some cancers.
Type: Peptide.
Definition (National Library of Medicine)
“A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It is also an endogenous neurotransmitter in many animals including mammals. Bombesin affects vascular and other smooth muscle, gastric secretion, and renal circulation and function.”
- MeSH: Bombesin
Human research
The registered human trials and peer-reviewed human studies linked below are listed from ClinicalTrials.gov and PubMed. A study is linked only when Bombesin is one of its interventions, or is named in the study title or subject headings.
Listing a study does not mean it showed a benefit, and it is not medical advice.
Registered human trials (10)
Peer-reviewed studies (35)
More cited research
- Insulinotropic action of bombesin-like peptides mediated by gastrin-releasing peptide receptors in steers (2016, human RCT)
- Bombesin-like peptides stimulate growth hormone secretion mediated by the gastrin-releasing peptide receptor in cattle (2012, human RCT)
- Electron immunocytochemical demonstration of serotonin, vasoactive intestinal polypeptide, bombesin, somatostatin and glucagon in mirror biopsies from primary c (2004, human observational)
- Neuroendocrine carcinoma of the ampulla of vater. A case of absence of somatostatin in a vasoactive intestinal polypeptide-, bombesin-, and cholecystokinin-prod (1991, human case report)
- Anatomical characterization of bombesin receptor subtype-3 mRNA expression in the rodent central nervous system (2013, animal)
- Identification of a unique ligand which has high affinity for all four bombesin receptor subtypes (1998, animal)
- Involvement of bombesin in spermine-induced corticosterone secretion and intestinal maturation in suckling rats (1997, animal)
- Bombesin does not stimulate pepsinogen release in isolated gastric chief cells (1995, animal)
Conditions researched
- Delayed gastric emptying on GLP-1 medicines
- Gallbladder and gallstones
- Immune system (general)
- Insulin resistance, prediabetes & type 2 diabetes
- Post-surgical inflammation and surgery recovery
Related compounds
- Calcitonin
- Insulin (regular human)
- Octreotide
- Peptide YY
- Somatostatin
- Exenatide
- GIP (Gastric Inhibitory Polypeptide)
- Ghrelin
- Glucagon
- Liraglutide
FAQ
What is Bombesin?
A 14-amino-acid peptide first found in frog skin; its analogs are studied as imaging tracers for some cancers.
How many registered human trials study Bombesin?
The PeptideWhiz trial index lists 10 registered trials for Bombesin, the most recent from 2022.
How much published research exists on Bombesin?
The PeptideWhiz paper index links 35 PubMed papers to Bombesin; by study type, 103 human and 304 animal studies.
Which conditions is Bombesin researched for?
Delayed gastric emptying on GLP-1 medicines, Gallbladder and gallstones, Immune system (general), Insulin resistance, prediabetes & type 2 diabetes, Post-surgical inflammation and surgery recovery.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).