What is Humanin?
A mitochondrial-derived peptide first identified through cytoprotection research; the published work is largely preclinical.
Humanin in the library · · Human Trials · What are peptides?
0 registered trials · 9 indexed papers · 154 human / 246 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
Humanin is described as a mitochondrial-derived peptide first identified through cytoprotection research. Later reviews discuss mitochondrial signaling, stress responses, metabolism, cardiovascular biology and aging-related models.
Peer-reviewed studies (9)
More cited research
- Assessment of mitochondrial peptide humanin in women with polycystic ovary syndrome: serum and skeletal muscle profile (2026, human observational)
- Circulating Humanin Improves the Prognostic Accuracy of Cardiovascular Risk Models in Chronic Hemodialysis Patients (2026, human observational)
- Diagnostic Value of Serum Humanin-Like 3 Levels in Multiple Sclerosis Patients with Predominant Optic Nerve and Spinal Cord Involvement: A Preliminary Study (2026, human observational)
- Diagnostic potential of serum humanin in breast cancer among the Egyptian population (2026, human observational)
- A mitochondrial-derived peptide MOTS-c contributes to the protective effect against brain injury associated with LPS-induced sepsis by strengthening the blood-b (2026, animal)
- Humanin Attenuates Inflammatory Liver Injury and NF-κB Activation During Systemic Hypervirulent Klebsiella pneumoniae Infection (2026, animal)
- Humanin Restores Metabolic Hormone Homeostasis of Leptin, Ghrelin, Irisin and Asprosin in Streptozotocin-Induced Diabetic Mice (2026, animal)
- Humanin ameliorates diabetes-induced testicular damage in a streptozotocin-induced mouse model (2026, animal)
Conditions researched
- Atherosclerosis, cardiovascular disease & high blood pressure
- Chronic and systemic inflammation
- Cognition, focus & brain performance
- Dementia, Alzheimer's & cognitive decline
- Eyes: macular degeneration & retinal health
- Insulin resistance, prediabetes & type 2 diabetes
- Sleep problems (incl. insomnia on peptides)
Related compounds
- Cyanocobalamin (Vitamin B12)
- BNP (Nesiritide)
- Glutathione
- Insulin (regular human)
- L-Carnitine
- MOTS-c
- ACTH (Corticotropin)
- Ghrelin
- IGF-1 LR3
- Methylene blue (non-peptide stack partner)
FAQ
What is Humanin?
A mitochondrial-derived peptide first identified through cytoprotection research; the published work is largely preclinical.
How many registered human trials study Humanin?
The PeptideWhiz trial index lists 0 registered trials for Humanin.
How much published research exists on Humanin?
The PeptideWhiz paper index links 9 PubMed papers to Humanin; by study type, 154 human and 246 animal studies.
Which conditions is Humanin researched for?
Atherosclerosis, cardiovascular disease & high blood pressure, Chronic and systemic inflammation, Cognition, focus & brain performance, Dementia, Alzheimer's & cognitive decline, Eyes: macular degeneration & retinal health, Insulin resistance, prediabetes & type 2 diabetes, Sleep problems (incl. insomnia on peptides).
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).