What is N-Acetyl Epitalon Amidate?
Epitalon (Ala-Glu-Asp-Gly) with an acetyl cap and amide end, sold as a more stable variant; human data exist only for plain Epitalon.
N-Acetyl Epitalon Amidate in the library · Bioregulator Peptides · Human Trials · What are peptides?
0 registered trials · 0 indexed papers · 16 human / 89 animal studies
From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
N-Acetyl Epitalon Amidate is described as a modified version of the tetrapeptide Epitalon, which has its own page. The changes aim to slow enzyme breakdown.
Mechanism (as described)
- The proposed mechanism is the same as Epitalon (telomerase and pineal-related research); no published work tests the modified form.
Evidence (as described)
- No study of the acetylated amidated form is on file. A 2025 review summarizes Epitalon research overall (Araj et al., 2025).
Status
Not approved.
More cited research
- LCP2 mediates SUV39H1-driven cellular senescence-related chemoresistance in natural killer/T-cell lymphoma (2026, human observational)
- Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity (2025, human observational)
- Short Peptides Protect Fibroblast-Derived Induced Neurons from Age-Related Changes (2024, human observational)
- EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE "OLD" CHROMATIN (2023, human observational)
- Epitalon-activated telomerase enhance bovine oocyte maturation rate and post-thawed embryo development (2025, animal)
- Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro (2022, animal)
- Effects of Geroprotectors on Age-Related Changes in Proteolytic Digestive Enzyme Activities at Different Lighting Conditions (2015, animal)
- [Main mechanisms of rhabdomyolysis-caused kidney injury and their correction by organospecific peptides] (2014, animal)
Related compounds
- Thymalin
- Thymulin
- ACE-031
- ACTH (Corticotropin)
- ANP (Atrial Natriuretic Peptide)
- Adrenomedullin
- Alpha-MSH
- Amycretin
- Amylin (Islet Amyloid Polypeptide)
- Anamorelin (non-peptide)
FAQ
What is N-Acetyl Epitalon Amidate?
Epitalon (Ala-Glu-Asp-Gly) with an acetyl cap and amide end, sold as a more stable variant; human data exist only for plain Epitalon.
How many registered human trials study N-Acetyl Epitalon Amidate?
The PeptideWhiz trial index lists 0 registered trials for N-Acetyl Epitalon Amidate.
How much published research exists on N-Acetyl Epitalon Amidate?
By study type, PeptideWhiz counts 16 human and 89 animal studies on N-Acetyl Epitalon Amidate.
Which conditions is N-Acetyl Epitalon Amidate researched for?
No condition pages are linked to this compound yet.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).