From the PeptideWhiz library entry. "As described" sections summarize claims made in the sources; they are not PeptideWhiz endorsements.
What it is
A peptide hormone family that acts on the heart and blood vessels; studied as an infusion in heart and lung research.
Type: Peptide.
Definition (National Library of Medicine)
“A 77 amino acid secreted endogenous ligand for the angiotensin II receptor-like 1 protein (apelin receptor) that is proteolytically cleaved into four smaller peptides: Apelin-36, Apelin-31, Apelin-28, and Apelin-13. It inhibits entry of HIV into cells that express both apj and cd4 antigen and is highly expressed in breast milk, where it may modulate the neonatal immune response.”
MeSH: Apelin
Human research
The registered human trials and peer-reviewed human studies linked below are listed from ClinicalTrials.gov and PubMed. A study is linked only when Apelin is one of its interventions, or is named in the study title or subject headings.
Listing a study does not mean it showed a benefit, and it is not medical advice.
A peptide hormone family that acts on the heart and blood vessels; studied as an infusion in heart and lung research.
How many registered human trials study Apelin?
The PeptideWhiz trial index lists 14 registered trials for Apelin, the most recent from 2024.
How much published research exists on Apelin?
The PeptideWhiz paper index links 70 PubMed papers to Apelin; by study type, 75 human and 20 animal studies.
Which conditions is Apelin researched for?
Atherosclerosis, cardiovascular disease & high blood pressure, Chronic and systemic inflammation, Concussion, traumatic brain injury & stroke recovery, Fat loss, obesity & body recomposition, Gum disease (periodontal) & oral health, Heart repair: after heart attack, heart failure & enlarged heart, High cholesterol and statins, Insulin resistance, prediabetes & type 2 diabetes, Kidney protection (CKD, diabetic kidney, lupus kidney), Low blood pressure and orthostatic hypotension, Muscle gain, sarcopenia & building muscle after 40, PCOS, Pregnancy and breastfeeding: safety notes, Rheumatoid arthritis, Thyroid problems.
Research and education only. Not medical advice. No dosing guidance. Data: ClinicalTrials.gov registry and PubMed via the PeptideWhiz index (204,289 studies).